政府奖惩机制下药品安全质量监管三方演化博弈及仿真分析

药品安全关乎人民群众生命健康、经济发展、社会稳定和国家安全，一直以来都是政府和全社会关注的热点问题之一。但是，近年来频发的各类药品安全事件，揭露了政府监管缺失、药品检测机制不完善、公众投诉失效等诸多问题。本文考虑了药品检测中存在寻租现象，构建了药品生产企业、第三方药品检测机构和政府监管部门之间的三方演化博弈模型，分析了各参与方策略选择的演化稳定性，探讨了各要素对三方策略选择的影响关系，进一步分析了三方博弈系统中均衡点的稳定性。研究结果表明：1)政府增强奖励、惩罚力度均有助于促进企业生产高药效药品、第三方药品检测机构拒绝寻租的规范行为，但是增大奖励力度将不利于政府自身履行监管职责；2)政府设定合理的奖惩机制必须符合对各方的奖惩之和大于其投机收益的条件，才能保障演化稳定市场环境下的药品安全；3)上级政府对监管部门失职的问责对增强企业生产高药效药品的稳健性具有重要意义；4)提升企业的药品销售收益、增加企业寻租成本也是避免企业生产低药效药品的有效途径。最后，利用Matlab 2020b进行了仿真分析，为政府完善药品监管机制提出了对策与建议。     

论生态环境损害赔偿诉讼与环境公益诉讼之衔接

在现行司法实践中,我国对生态环境损害之救济采取的是生态环境损害赔偿诉讼与环境公益诉讼并行的"双轨制"模式.通过分析典型案件可以发现,现行立法未能为化解生态环境损害赔偿诉讼与环境公益诉讼之间的制度"碰撞"提供明确的规范指南,导致"两诉"之间时常会陷入管辖冲突与衔接困境.生态环境损害赔偿诉讼的模糊属性以及相关立法规定的缺失,是导致"两诉"衔接陷入困境之根由.为此,应当在准确识别生态环境损害赔偿诉讼性质之前提下,通过立法对"两诉"之间的顺位规则、索赔主体机制等核心规范予以明确.具体而言,未来我国应当明确生态环境损害赔偿诉讼优于环境公益诉讼的顺位规则,并建立"行政机关—环保组织—检察机关"三位一体且逐层递进的索赔主体结构,最大程度发挥"两诉"之制度合力.     

域外植物的输入与中古社会

大量域外植物入华是汉武帝时代丝路开通后的结果,外来的植物引种在魏晋南北朝时得到推广。域外传入的植物用途主要有观赏、食用和用作香料、医药等方面,域外植物的引进改变了中国人的膳食结构,丰富了饮食文化,提高了人们的生活水平,对于中国中古社会的农业生产、饮食文化、医学医药、民间信仰和文学艺术产生了积极影响。有关种植技术的记载出现在魏晋南北朝时期的著述中,反映了这些外来植物在这一时期广泛种植并积累了丰富经验的实际情况。域外植物的种植推动了商品经济的发展。     

Causal dynamics of poverty reproduction in EU countries

This study investigated causal mechanisms of poverty reproduction in EU countries by placing emphasis on the parental background effect on sons’ poverty risk after having controlled for endogeneity among observable and non‐observable effects of the involved mechanisms. The countries under investigation were old EU member states representing the four welfare regimes in the EU. Having employed path models and utilised EU‐SILC 2005 data, the analysis yielded no statistically significant direct effect of parental background on sons’ poverty risk in Denmark. Greece, however, exhibited a statistically significant and quite strong direct effect. Germany and the United Kingdom stood in‐between. Moreover, the analysis found indirect channels through which the parental background affects sons’ poverty risk. These findings are expected to enrich the academic discourse and inform the policy‐making process on poverty reproduction and social protection in the EU.     

Multivariate Return Decomposition: Theory and Implications

In this paper, we propose a model based on multivariate decomposition of multiplicative – absolute values and signs – components of asset returns. In the m-variate case, the marginals for the m absolute values and the binary marginals for the m directions are linked through a 2m-dimensional copula. The approach is detailed in the case of a bivariate decomposition. We outline the construction of the likelihood function and the computation of different conditional measures. The finite-sample properties of the maximum likelihood estimator are assessed by simulation. An application to predicting bond returns illustrates the usefulness of the proposed method.     

Elementary School-age Children's Attitudes Toward Children in Same-Sex Parent Families

As numbers of families with same-sex parents increase in the United States, children are more likely to encounter diverse family structures. Given that young children can demonstrate in-group bias, prejudicial attitudes, and social exclusion, it is important to understand how children perceive their peers in diverse families. To our knowledge, no studies have assessed elementary-school-age children's attitudes about same-sex parent families. Here, 131 elementary school students (M_age = 7.79 years; 61 girls) viewed images of same-sex (female and male) and other-sex couples with a child and then were asked about their perceptions of these families, particularly the children. Results indicated participants' preferences toward children with other-sex versus same-sex parents. Developmental and practical implications about children's attitudes toward sexual minority parent families are discussed.     

Effect of cigarette smoking on sexual functions,psychological factors,and disease activity in male patients with ankylosing spondylitis

Objective: This study aims to investigate the effect of smoking on sexual functions in AS patients.

Patients and methods: A total of 67 male AS patients with a median age of 34 years (range: 18–57) reporting sexual activity at least for the past 4 weeks period were included. Patients were divided into smokers (Group 1, n?=?47) and non-smokers (Group 2, n?=?20). Fagerström test for nicotine dependence, smoking history, exhaled carbon monoxide test were recorded for smoking AS patients. Visual analogue scale (VAS), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Metrology Index (BASMI), Bath Ankylosing Spondylitis Functional Index (BASFI), Ankylosing Spondylitis Quality of Life (ASQoL), International Index of Erectile Function (IIEF), Beck Depression Inventory (BDI) were filled for both groups.

Results: There was no significant difference between smokers and non-smokers in all evaluation parameters. BASMI scores were significantly lower in the mild dependency subgroup as compared to those with moderate or severe dependency (p?=?.005 and p?=?.007, respectively). Total IIEF score and IIEF categories correlated significantly with BASDAI, BASFI, BASMI, ASQoL, pain, fatigue, and cumulative smoking. BDI showed an inverse correlation with the IIEF score and IIEF category (p?r?=?–0.520, p?r?=?–0.508, respectively).

Conclusions: Sexual function in AS patients is associated with the pain, fatigue, disease activity, functional status, quality of life, depression as well as the cumulative exposure to smoking, and that sexual functions tend to decline with increasing degree of cigarette dependency.     

滕尼斯与齐美尔:社会伦理同文化伦理的分流

作为德国社会学的两位奠基人，滕尼斯和齐美尔奠定了截然相反的两种现代伦理生活格局。伦理世界观的分流源于他们各自对时代处境的体验以及对思想史的独特解释。从近代自然法的角度出发，滕尼斯的社会伦理的核心是重建政治社会的秩序与风尚，一切价值最终都要融入社会；与此相反，齐美尔的社会学思考从一开始就以对社会伦理的批评作为前提，他将超越社会的个体生命视作伦理的目的，对他来说，生命不仅意味着身处社会之中的个体具有饱满个性，而且从自身孕育出客观的、适用于他自己的伦理责任。从帝制时期到魏玛时期，德国社会伦理同文化伦理的分流、交织与合流为我们提供了一条理解德国社会学史的清晰主线。     

Dependence and uncertainty in broker strategies of research intermediaries

This study examines how a research intermediary can successfully manage collaboration among research partners, while mitigating resource dependence in multi-partner programs. For that purpose, two fundamentally different strategies are explored: tertius gaudens and tertius iungens. Previous literature has not addressed the possibility that the effective deployment of tertius broker strategies may be contingent on multiple factors. Using a qualitative in-depth case study, we contribute to the literature by showing that the effective development of the tertius broker strategies in our study context is contingent on partner type, business integration and product readiness.     

高等教育布局结构优化的理论前提

作为经济社会发展的重要助推力量,高等教育布局结构优化的影响因素是多维的,主要包括国家战略、区域经济、社会文化、人口结构以及地理空间等等。科学预设高等教育布局结构优化的应然目标,需要正视布局结构优化的目标限度,并重点从“社会满足度”和“个体满足度”两个方面予以考量。实施高等教育布局结构的优化,需要甄选多向度的优化理路,实现多元布局手段的优势集合。要坚持“去趋同化与优势集中相统整”“域内均衡与域间协调相统整”“突显公平与保障效益相统整”“积极适应与适当超越相统整”“内循规律与外在干预相统整”等原则。